Notably, YY1 encodes the protein yin and yang 1, a zinc-finger TF known to be important in central nervous system myelination by interacting with dystonia-associated gene THAP1 (Baumann et al., 2021; Domingo et al., 2021; Yellajoshyula, et al., 2022; Zorzi et al., 2021). Here, THAP1 is linked to Dystonia.