The critical role of TGF-β1 was further emphasized by the ability of TGF-β1 soluble receptors (Yata et al. 2002) or TGF-β neutralizing antibody to scavenge TGF-β1 and reverse hepatic fibrosis in experimental animals (Ling et al. 2013). This evidence concerns the gene TGFB1 and Hepatic fibrosis.