By implanting molecular docking, It was shown DAs extracted from Delphinium trichophorum (DTF), especially DTF1 and DFT2, hamper TGF‐β/ SMAD pathway and protect against PF in various ways, including interaction with TGFB receptor 1 (TGFBR1) and covering it, downregulating TGF‐β1 and α‐SMA, and restoring Smad7, the inhibitory Smad89 (Figure 2A). The gene discussed is TGFB1; the disease is pemphigus foliaceus.