Under US irradiation (1.5 MHz, 1.5 W cm−2, 5 min), ZGO@TiO2@ALP could not only eradicate the primary tumors and inhibit the formation of metastasis, thereby significantly improving survival (Figure 12c), but also prevent tumor recurrence (Figure 12d), which illustrates that the combined strategy triggers antitumor memory immunity.[127] This multifunctional nanoplatform can make up for the defects of chemotherapy and anti‐PD‐1 therapy, which is both effective and low toxicity. This evidence concerns the gene PDCD1 and neoplasm.