Part of the reason for tumor suppression may be attributed to the fact that tumor necrosis could activate ICD‐induced antitumor immune response.[59] In addition, as shown in Figure2a, nitric oxide (NO) release nanoparticles, SNO‐HSA‐PTX, loading chemotherapeutic drug, paclitaxel (PTX), could release NO under US irradiation, inducing the blockade of platelets in tumor‐bearing mice. Here, ALB is linked to neoplasm.