In accordance with expectation, cMn‐MOF@CM‐mediated synergistic therapy of SDT (US parameters: 1.0 MHz, 1.5 W cm−2, 50% duty cycle, 5 min) and anti‐PD‐1 caused a systemic immune response and long‐term immune memory function, effectively preventing tumor growth and recurrence.[123] Consequently, SDT‐induced ICD‐based antitumor immune response has the ability to augment the efficiency of ICB therapy, which can amplify systemic antitumor immunity, and stimulate memory immunity. This evidence concerns the gene PDCD1 and neoplasm.