ARHGAP1 was the first gene discovered in this family, and its content in cervical cancer cells and Ewing Sarcoma (ES) cells was lower than that in the matching normal tissue, which proved that it could inhibit the cell vitality, cell migration, and invasion of these two cancer cells in a time-dependent manner to a certain extent [25, 26]. This evidence concerns the gene ARHGAP1 and Ewing sarcoma.