In terms of CKD/ESKD kidney function, urine TIMP-1, β2-microglobulin, NGAL, cystatin C, VEGF-A, IP-10, RBP4 and GSTA1 positively correlated with creatinine, whereas Uromodulin and EGF negatively correlated with creatinine. The gene discussed is GSTA1; the disease is chronic kidney disease.