We were unable to detect pUL16 and pUL21 binding to incoming capsids when pUL16 and pUL21 were ectopically expressed prior to infection (Fig 5), suggesting that pUL16 and pUL21 interference with capsid/NPC interactions does not involve pUL16 or pUL21 binding to capsids. This evidence concerns the gene NPC1 and infection.