Compared with the abundance in the low-risk group, the abundance of CD4 T cell, neutrophil and macrophage was significantly reduced in the high-risk group (S1A Fig). Among the 8 immune cells analyzed by EPIC, B cell, cancer associated fibroblast, endothelial cell and macrophage showed significantly lower abundance levels in the high-risk group than in the low-risk group (S1B Fig). The gene discussed is CD4; the disease is cancer.