Carriers of two polymorphic E2F2 rs2075995 alleles were less likely to develop MM (OR = 0.64, 95% CI = 0.43–0.96, P = 0.032), but the association was no longer significant after adjustment for age (OR = 0.68, 95% CI = 0.44–1.07, P = 0.093). Here, E2F2 is linked to Miyoshi myopathy.