Alpha/beta‐hydrolase domain containing 5 (ABHD5), a key enzyme in lipolysis regulating tumor biology29 and toll‐like receptor 4 (TLR4), induced by fatty acids and mediating nuclear factor‐κB (NFκB) pathways, both also play an important role in TAM‐mediated tumor progression.30 Here, TLR4 is linked to neoplasm.