Statistical analysis was conducted on the clinical data of 40 patients, revealing no statistically significant differences in the distribution of PLK1 and p-PLK1 expression among NKTCL patients with regard to gender, age, Ann Arbor stage, PINK-E score, B-symptoms, lactate dehydrogenase, β2-microglobulin, blood EBV-DNA, bone marrow invasion, and lymph node metastasis (p > 0.05). Here, PLK1 is linked to metastatic malignant neoplasm in the lymph nodes.