ERBB2 and breast carcinoma: Moreover, investigation of SCEL expression in a series of breast cancer cell lines including luminal subtype (MCF-7 and T-47D), HER2 subtype (SK-BR-3 and HCC1419), and TNBC subtype (MDA-MB-468, BT-549, Hs578T), revealed that SCEL is specifically expressed in the long-term metastatic lung nodules-derived LC subline (Fig. 3A).