By analyzing the TCGA database, we determined that there were significant differences in the activity of ATP7B between 16 types of cancer tissues and normal tissues, including BRCA, COAD, GBM, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, PAAD, PCPG, PRAD, STAD, THCA, UCEC (Fig. 7C). The gene discussed is ATP7B; the disease is cancer.