It was also found that in resectable cases, the rate of TP53 missense mutation was higher in large-sized (> 3 cm) tumors (48.3% vs. 36.9% in small-sized tumors, P = 0.083), as shown in Additional file 4: Table S9_Frequency of Core Gene Pathway Alterations according to Tumor Size in KRASmut PDAC. The gene discussed is TP53; the disease is neoplasm.