More recently, a meta-analysis was performed in 16 case study to investigate the link between the GRN polymorphism at rs5848 with neurodegenerative diseases, such as FTD, AD, PD, and ALS [14], and the authors conclude that the polymorphism at rs5848 is associated with a higher risk of AD and PD. The gene discussed is GRN; the disease is amyotrophic lateral sclerosis.