Results of the top 20 KEGG annotations of DEmiRs are shown in Fig. 4B, such as Fc gamma R-mediated phagocytosis, Inflammatory bowel disease IBD, mTOR signaling pathway, Renal cell carcinoma, Bile secretion, etc. According to disease ontology analysis, DEmiRs might mediate five ovarian-related diseases, including Ovarian clear cell carcinoma, Ovarian Neoplasms familiar, Ovarian carcinoma, and Ovarian epithelial cancer (Fig. 4C). The gene discussed is MTOR; the disease is renal cell carcinoma.