We then collected primary mononuclear cells from two umbilical cord blood samples (Normal #1, Normal #2), primary bone marrow mononuclear cells from two AML patients diagnosed with none FLT3-ITD mutation AML (AML #1, AML #2) and three AML patients harboring FLT3-ITD mutation (AML #3, AML #4, AML #5) to extensively evaluate the anti-FLT3-ITD AML activity of GNF-7. This evidence concerns the gene FLT3 and acute myeloid leukemia.