As a result, the enriched KEGG pathways of dysregulated miRNAs were frequently associated with signal transduction such as Wnt signaling pathway, FoxO signaling pathway, TGF-beta signaling pathway, Hippo signaling pathway, mTOR signaling pathway and MAPK signaling pathway, tumorigenesis such as proteoglycans in cancer, colorectal cancer, pancreatic cancer, prostate cancer and bladder cancer, endocytosis and fatty acid metabolism (full list in Table S3). The gene discussed is MTOR; the disease is familial pancreatic carcinoma.