The logistic regression analysis was used to evaluated the predictive value of a panel including 2 miRNA-mRNA regulator pairs: miR-139-5p/ STC1 and miR-20a-5p/ FGL2 in testing cohorts GSE35602, GSE126095 and GSE12844, and validation cohort containing 80 CRC tissues by qRT-PCR. Here, FGL2 is linked to colorectal carcinoma.