Exosomal miR-17-5p derived from adipose-derived mesenchymal stem cells (ADSCs) decreased thioredoxin-interacting protein-induced pyroptosis in macrophages induced by Ang II, and the overexpression of miR-17-5p enhanced the therapeutic potential of ADSC-derived exosomes in an AAA mouse model118. The gene discussed is AGT; the disease is triple-A syndrome.