SETD7 (also known as SET7, SET9, or SET7/9) is highly expressed in hepatocellular carcinoma and colorectal cancer tissues compared to noncancerous tissues, and the increased expression of SETD7 was found to be closely correlated with cancer progression via regulation of cell proliferation and metastasis in these cancers28,29. This evidence concerns the gene SETD7 and colorectal cancer.