In BD-Lithium and BD-OD groups, when compared to the control group, we observed a significantly lower expression of TLR4 (p = 0.0002 and p < 0.0001, respectively), NLRP3 (p = 0.002 and p = 0.014, respectively), CASP4 (p = 0.015 and p = 0.005, respectively) and significantly higher expression of IL1A (p < 0.001 and p = 0.002, respectively). This evidence concerns the gene CASP4 and Behcet disease.