PPP1R1B and neoplasm: Low nuclear DARPP-32 Thr-34 phosphorylation was significantly associated with a moderate tumour stage (χ2 = 8.644, d.f. = 2, P = 0.013), and positive lymph node status (χ2 = 8.541, d.f. = 1, P = 0.003) at the time of presentation (Table 2).