Consistent with our analysis of the preventive effect of DLPC, we found that DLPC-treated DIO mice showed improved glucose intolerance (Fig. 6d, Supplementary Fig. 10b, c) and insulin sensitivity (Fig. 6e, Supplementary Fig. 10d, e), as well as decreases in the serum levels of T-CHO and LDL-C (Fig. 6f, g). The gene discussed is INS; the disease is Glucose intolerance.