Mutations and copy number variants in neurexins are associated with characteristic changes in human behavior [13], and variation in the NRXN1 gene is genetically associated with autism spectrum, Tourette syndrome, schizophrenia, developmental delay, intellectual disability, obsessive compulsive disorder, epilepsy, attention deficit and hyperactivity disorder, and Pitt Hopkins Syndrome 2 [13–16]. This evidence concerns the gene NRXN1 and Tourette syndrome.