APOL1 and kidney disorder: In fact, APOL1 G2-HR donors who are p.N264K positive will likely have kidney outcomes similar to any of the G1G0, G2G0, and G0G0 low-risk donors, thus expanding donors’ pool; kidney transplant recipients of a APOL1-HR-p.N264K kidney will likely have low risk for developing de novo FSGS on the graft or graft failure from APOL1-associated kidney disease.