Around the connecting cilium, all along the microtubule doublets, are found the Y-links, specialized macromolecular structures hypothesized to be made partially of CEP290 (Fig. 5f), a protein crucial for proper photoreceptor function and of which mutations have been linked to eye diseases such Leber Congenital Amaurosis that causes childhood blindness42–44. This evidence concerns the gene CEP290 and eye disorder.