Mice treated with anti-PD-1 and FMT also showed higher amounts of aspirin, which inhibits the growth of CRC-associated bacterium F. nucleatum, and punicic acid, which elicits anti-tumor effects (Mete et al., 2019; Brennan et al., 2021; Yuan et al., 2021; Huang et al., 2022). This evidence concerns the gene PDCD1 and neoplasm.