TH and Parkinson disease: PD mice were treated with SC injections of 2.5–5 mg/kg of the TXB4-TrkB BSA, or the 29D7 MAb alone, at −1 and + 7 days relative to toxin injection in brain, and were euthanized at 14 days after toxin injection for measurement of immunoreactive TH in the substantia nigra.