MYO6 and diffuse large B-cell lymphoma: To overcome the low abundance and integrity of RNA content on formalin-fixed paraffin embedded (FFPE) biopsy samples, we adopted an implemented quantitative multiplex droplet digital PCR-based assay (Figure 1C; Figure 2A), from which emerged that two out ten DEGs, previously identified, EBF1 and MYO6 resulted up-regulated, at both mRNA and protein levels, in responder DLBCL patients (Figures 2B–D; Supplementary Figures 2A, B; Supplementary Table 3).