Exposure to GBS led to the secretion of IL-1β, IL-6, IL-10, IL-12p70, IL- 18, IL-21, IL-22, IL-23, and RANTES/CCL5, but not IL-1RA, IL-8/CXCL8, IL-20, IL-27, IFN-β, MCP-1/CCL2 and MIF in newborn and adult MDMs. Here, IL21 is linked to Guillain-Barre syndrome.