Consequently, the following points were assigned: overdose (2 points), rivaroxaban (2 points), anemia (1 point), CrCl <30 mL/min (2 points), RYR2 rs12594GG (2 points), rs17682073 AA (1 point), rs6678625 T allele (2 points), and rs3766871GG (3 points). This evidence concerns the gene RYR2 and anemia.