Consistent with our investigation, the suppression of RBBP4 impeded the proliferation, invasion, and migration of triple-negative breast cancer cells by modulating the epithelial-mesenchymal transition (Zheng, Yao & Liu, 2022), while the promotion of colon cancer progression was facilitated by RBBP4 through the augmentation of the Wnt/ β catenin pathway (Li, Lv & Zhu, 2020). Here, RBBP4 is linked to malignant colon neoplasm.