The best cut-off value of DBS MMP-7 in the diagnosis of BA at −80 °C was 12.5 ng/ml, achieving the AUC of 0.922 (95% CI: 0.888, 0.956), and the sensitivity, specificity, PPV, and NPV were 86.9%, 89.0%, 94.8%, and 74.7%, respectively (Figure 2C). This evidence concerns the gene MMP7 and breast angiosarcoma.