AKT1 and atherosclerosis: The KEGG enrichment analysis identified 165 signaling pathways and revealed that 213 predictive targets were predominantly associated with phosphoinositide 3-kinase-protein kinase B (PI3K-AKT) signaling pathway, proteoglycans in cancer, the Ras signaling pathway, the calcium signaling pathway, chemical carcinogenesis receptor activation, lipid and atherosclerosis, apoptosis and other signal pathways (Fig. 4B).