No significant differences were found (P > 0.05) in terms of age, gender, NIHSS score, dysphagia, encephalanalosis, hypertension, diabetes, hyperlipidemia, COPD, CHD, atrial fibrillation, cardiac insufficiency, renal insufficiency, hepatic insufficiency, FBG, CRP, WBC, NEUT%, HB, PLT, albumin, prealbumin, triglyceride, TC, LDL, homocysteine, K+ and Na+ between two groups. The gene discussed is TTR; the disease is Renal insufficiency.