Our results indicated that: age (Elderly), NIHSS score (High), dysphagia (Yes), atrial fibrillation (Yes), cardiac insufficiency (Yes), renal insufficiency (Yes), hepatic insufficiency (Yes), FBG (Abnormal), CRP (Upregulated), NEUT% (Upregulated) and prealbumin (Downregulated) were independent risk factors for the occurrence of AIS associated AP. This evidence concerns the gene TTR and atrial fibrillation.