Univariate analysis revealed significant differences (P < 0.05) in 20 baseline clinical characteristics, including age, gender, NIHSS score, dysphagia, hyperlipidemia, COPD, CHD, atrial fibrillation, cardiac insufficiency, renal insufficiency, hepatic insufficiency, FBG, CRP, WBC, NEUT%, HB, albumin, prealbumin, triglycerides and K+ between two groups, which were suspected influencing factors for AP in patients with AIS history. The gene discussed is CRP; the disease is Renal insufficiency.