AKT2 and non-small cell lung carcinoma: For example, Liu T. et al. (2020) showed that AKT2, playing a pro-oncogenic role in many human cancers, was a miR-124 downstream target gene and that overexpression of miR-124 in non-small cell lung cancer (NSCLC) led to downregulation of AKT2 and played a tumor suppressor role.