In addition, treating Huh7 cells (a hepatocyte-derived carcinoma cell line) with the HDAC3 inhibitor RGFP966 increased YAP immunofluorescence in the nucleus (Fig. S4A and B), and Western blot analysis confirmed that RGFP966 decreased YAP in the cytoplasm and increased YAP in the nucleus (Fig. S4C to F). Here, HDAC3 is linked to carcinoma.