GATA2 and Decreased total monocyte count: The critical role that GATA2 plays in GMP formation, myeloid differentiation and maturation easily explains the regulatory mechanisms behind the dendritic cell deficiency, monocytopenia, and neutropenia frequently observed in patients that have been diagnosed with GATA2 deficiency syndromes (Hsu et al., 2011; Spinner et al., 2014; Calvo and Hickstein, 2023).