In this study, most of the CaM/CML genes enriched in plant-pathogen interaction showed down-regulated expression, while two genes (Glyma.18G260700 and Glyma.09G236800) were up-regulated after viral infection (Figure 7), suggesting that CMLs in soybean act antagonistically in the regulation of induced defense responses. The gene discussed is BCR; the disease is viral infectious disease.