For example, infection with Rosellinia necatrix mycovirus 3 (RnMyRv3) or Rosellinia necatrix megabirnavirus 1 (RnMBV1) upregulates the expression of genes DCL2, AGO2, RDRP1, and RDRP2 in R. necatrix (Yaegashi et al., 2016). Here, AGO2 is linked to infection.