A study showed that AHNAK2 expression in lung adenocarcinoma was negatively correlated with activated B cells, activated CD8+ T cells and immature B cell infiltration, while it was positively correlated with central memory CD4+ T cells, tumor-associated macrophages, M1 macrophages and M2 macrophage infiltration, promising a new target for immunotherapy (53). Here, AHNAK2 is linked to neoplasm.