For AHNAK2, its expression was downregulated in BLCA, BRCA, COAD, GBM, PRAD, READ and UCEC while up-regulated in CHOL, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, PAAD, PCPG and THCA (Figure 4B). The gene discussed is AHNAK2; the disease is bladder transitional cell carcinoma.