Stimulation of ECs by Wnt family ligand 7B (WNT7B) aberrantly expressed in TAMs, which regulates the Wnt/β-catenin signaling pathway and VEGF production, and thereby triggers angiogenesis, tumor progression, growth, tumor cell invasion, and metastasis, was demonstrated in models of luminal breast cancer (73, 132, 133). Here, WNT7B is linked to neoplasm.