We further showed significant effect of hypertension on MoCA, F (1,196) = 8.52 (ES: 0.04; Mean: hypertensives = 21.34, non-hypertensives = 19.73), but no significant difference was found on diabetes, F (1,196) = 0.05 (ES: 0.001) as well as no interaction of hypertension and diabetes, F (1,196) = 2.64 (ES: 0.01). The gene discussed is DOCK3; the disease is hypertensive disorder.