APOBEC3A and hepatocellular carcinoma: This -2 pyrimidine bias mirrors original results from human A3A expression in yeast [50, 51], as well as recent WGS results from human A3A expression in the chicken B cell line DT40 (~70% YTCW [71]) and from human A3A-induced murine hepatocellular carcinomas (70% YTCW [70]).