Prior work with acute fluoxetine has also failed to find effects on AUC, reaction time or omission errors in those with ADHD utilising similar tasks to those employed in the current study [27], supporting this suggestion that treatments thought to impact on 5-HT, either through increased synthesis, and, therefore, release, or decreased reuptake, do not impact core symptoms as much as additional areas of impairment. The gene discussed is HTR5A; the disease is attention deficit-hyperactivity disorder.