For Pirin and its interaction partners, disease conditions correlated to pathogenic infections, such as Tuberculosis, Hepatitis B and viral diseases, as well as the body’s response to the infections, including regulation of actin dynamics for phagocytic cup formation and Fc gamma receptor (FCGR) dependent phagocytosis, are enriched (Figs 6 and 8). This evidence concerns the gene PIR and tuberculosis.