In this study, analysis of high-throughput RNA-seq data from the TCGA database confirmed that TUBA1C expression in breast cancer tissues was significantly higher than that in normal tissues, and the pairwise difference analysis between cancer and paired paracancerous tissues also showed that in cancer tissues, TUBA1C expression was significantly higher than that in paired paracancerous tissues. The gene discussed is TUBA1C; the disease is breast carcinoma.