Interestingly, among this group of genes, a subset of genes have been associated with T2D through SNPs (19), including TSHZ3 and WT1, which are increased in expression in I-Res iMyos, and PBX2, ZNF213, and IRF2BP1, which are decreased in expression in I-Res iMyos. Here, PBX2 is linked to type 2 diabetes mellitus.