There were 3842 patients with YO CRC (mean [SD] age, 41.97 [6.25] years), including 1546 patients with KRAS variants, and 17 819 patients with LO CRC (mean [SD] age, 66.93 [10.57] years), including 7311 patients with KRAS variants. Here, KRAS is linked to colorectal carcinoma.