However, comparisons of variant vs wild-type KRAS in the LO group showed no noticeable trend by tumor location from right (sHR, 0.97 [95% CI, 0.93-1.02]) to left (sHR, 1.15 [95% CI, 1.08-1.22]) and rectum (sHR, 1.10 [95% CI, 1.02-1.20]) (Figure 3). The gene discussed is KRAS; the disease is neoplasm.