In a murine model of CpG island methylator phenotype (CIMP) CRC, infection with Enterotoxic Fragile Bacteroides promoted the recruitment of IFN-γ-producing CD8 T cells, thereby enhancing the efficacy of anti-programmed cell death ligand 1 (Anti PD-L1) therapy [156]. This evidence concerns the gene CD274 and colorectal carcinoma.